A queen of Egypt, reigning c 1479-1457 BC in the 18th Dynasty. She was the daughter of Thutmose I (1504-1492 BC) and Queen Ahmose Nefertari, was married to her half-brother Thutmose II (1492-1479 BC). A strong ruler, she sent a trading expedition to Punt, as recorded in detail in her funerary temple. She was succeeded by her son Thuthmose III. Her reign was marked by peace, prosperity, and artistic achievement. Her funerary temple at Deir El-Bahri at Thebes is one of the most original and beautiful in Egypt.